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235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">Two-Dimensional Liquid Chromatography: Principles, Practice, and Applications\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Stephan Buckenmaier &amp; Dwight Stoll\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Full Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Saturday, June 6, 9:00 am - 4:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:solid;border-right-style:solid;border-top-style:none;border-width:0px;height:40.5pt;padding:0.75rem 1rem;\">2\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">Practical LC-MS/MS Method Development\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Perry Wang\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Full Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Saturday, June 6, 9:00 am - 4:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border:0px solid rgb(229, 231, 235);padding:0.75rem 1rem;\">3\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">Introduction to Artificial Intelligence for Liquid-phase Separations\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Tijmen Bos\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Full Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Saturday, June 6, 9:00 am - 4:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd>4\u003C/td>\u003Ctd>Analysis of Oligonucleotide Therapeutics\u003C/td>\u003Ctd>Claus Rentel\u003C/td>\u003Ctd>Full Day\u003C/td>\u003Ctd>Saturday, June 6, 9:00 am - 4:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:solid;border-right-style:solid;border-top-style:none;border-width:0px;height:15.5pt;padding:0.75rem 1rem;\">5\u003C/td>\u003Ctd style=\"border:0px solid rgb(229, 231, 235);padding:0.75rem 1rem;\">Supercritical Fluid Chromatography\u003C/td>\u003Ctd style=\"border:0px solid rgb(229, 231, 235);padding:0.75rem 1rem;\">Larry Miller\u003C/td>\u003Ctd style=\"border:0px solid rgb(229, 231, 235);padding:0.75rem 1rem;\">Half Day\u003C/td>\u003Ctd style=\"border:0px solid rgb(229, 231, 235);padding:0.75rem 1rem;\">Sunday, June 7, 9:00 am - 12:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:solid;border-right-style:solid;border-top-style:none;border-width:0px;height:14.5pt;padding:0.75rem 1rem;\">6\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">Sample Preparation and Extraction for LC Workflows\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Emanuela Gionfriddo\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Half Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Sunday, June 7, 1:00 - 4:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:solid;border-right-style:solid;border-top-style:none;border-width:0px;height:25pt;padding:0.75rem 1rem;\">7\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">(u)HPLC Method Development\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Michael Dong\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Half Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Sunday, June 7, 9:00 am - 12:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:solid;border-right-style:solid;border-top-style:none;border-width:0px;height:14.5pt;padding:0.75rem 1rem;\">8\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">Multi-Detector Size-Based Separations: SEC, HDC, and flow FFF\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;\">André Striegel\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;\">Half Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Sunday, June 7, 9:00 am - 12:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:solid;border-right-style:solid;border-top-style:none;border-width:0px;height:25pt;padding:0.75rem 1rem;\">9\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">Chiral Chromatography\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;\">Michael Lämmerhofer\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;\">Half Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Sunday, June 7, 1:00 - 4:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:solid;border-right-style:solid;border-top-style:none;border-width:0px;height:25pt;padding:0.75rem 1rem;\">10\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">Drug Development, Drug Quality, Regulatory, and Quality Control Processes\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Michael Dong\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Half Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Sunday, June 7, 1:00 - 4:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:solid;border-right-style:solid;border-top-style:none;border-width:0px;height:14.5pt;padding:0.75rem 1rem;\">11\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">Advanced chromatographic strategies for comprehensive characterization of protein biopharmaceuticals\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Davy Guillarme\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Half Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Sunday, June 7, 9:00 am - 12:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:solid;border-right-style:solid;border-top-style:none;border-width:0px;height:14.5pt;padding:0.75rem 1rem;\">12\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:227pt;\">Basic Theories and Practice of Hydrophilic Interaction Liquid Chromatography\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Yong Guo\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:120pt;\">Half Day\u003C/td>\u003Ctd style=\"border-bottom-style:solid;border-color:rgb(229, 231, 235);border-left-style:none;border-right-style:solid;border-top-style:none;border-width:0px;padding:0.75rem 1rem;width:89pt;\">Sunday, June 7, 1:00 - 4:00 pm\u003C/td>\u003C/tr>\u003Ctr>\u003Ctd>13\u003C/td>\u003Ctd>Advanced Topics in HPLC\u003C/td>\u003Ctd>James Grinias\u003C/td>\u003Ctd>Half Day\u003C/td>\u003Ctd>Sunday, June 7, 1:00 - 4:00 pm\u003C/td>\u003C/tr>\u003C/tbody>\u003C/table>\u003C/figure>",{"id":110,"__component":1603,"componentVariation":1604,"contactsVariation":1605,"styles":1606,"header":16,"sessionsGroup":1608},"content.sessions","Sessions Base","Card Contact Full",{"id":270,"edgeTop":92,"edgeBottom":92,"background":1607,"containerWidth":16},"base-50",[1609],{"id":110,"groupTitle":1610,"sessions":1611},"Short Course Descriptions",[1612,1694,1734,1767,1819,1852,1902,1929,1961,2015,2029,2061,2095],{"id":110,"session":1613},{"id":110,"title":1614,"teaser":1615,"body":1616,"createdAt":1617,"updatedAt":1618,"publishedAt":1619,"url_path_id":1620,"contacts":1621,"url_path":1693},"Two-Dimensional Liquid Chromatography: Principles, Practice, and Applications","\u003Cp style=\"text-align:justify;\">Many industries are developing increasingly complex products, whose separation requires substantially more resolving power than that offered by state-of-the-art one-dimensional liquid chromatography. Two-dimensional liquid chromatography (2D-LC) techniques meet that need and are finding ever more application to the analysis of samples of moderate to high complexity.\u003C/p>","\u003Cp>This course will cover:&nbsp;\u003C/p>\u003Cul>\u003Cli>Concepts of the technique including the theoretical underpinnings of the advantages of 2D separations over their conventional 1D-LC counterparts.&nbsp;\u003C/li>\u003Cli>Practical aspects of modern 2D-LC that are critical for the development of successful separations including experimental details, column selection, and the management of the interface between the two separation dimensions.\u003C/li>\u003Cli>Applications of 2D-LC described in the literature that address problems in a variety of industries ranging from the analysis of small molecular weight compounds to polymers, which can be chemical as well as biological in nature.\u003C/li>\u003Cli>Recent trends towards MD-LC that, by adding further dimensions, allow for deep insights into the structure of biomolecules and have the potential for more automation in analytical workflows.\u003C/li>\u003C/ul>","2025-12-29T16:12:06.431Z","2025-12-29T16:12:41.710Z","2025-12-29T16:12:41.703Z","83",[1622,1652],{"id":325,"name":1623,"committee":16,"position":16,"affiliation":1624,"email":16,"biography":1625,"createdAt":1626,"updatedAt":1626,"url_path_id":1627,"contactPhoto":1628,"socialLinks":1650,"url_path":1651},"Stephan Buckenmaier","Agilent Technologies","\u003Cp style=\"text-align:justify;\">Dr. Stephan Buckenmaier is Principal Scientist in R&amp;D at Agilent Technologies, specializing in advanced separation sciences. In recent years, he has led the development of Two-Dimensional Liquid Chromatography (2D-LC) solutions. His work also embraces fostering collaborations with industry partners and academic institutions, education in separation science, and mentoring colleagues. Stephan joined Agilent in 2006 as a Scientist focused on LC/MS applications for pharmaceutical analysis. Before that, he was a Postdoctoral Researcher at the Proteome Center at the University of Tübingen, studying diagnostic proteins and post-translational modifications. He earned his Ph.D. from the University of the West of England (Bristol, UK) in 2004, investigating factors influencing retention and peak shape in reversed-phase HPLC under the guidance of Prof. David McCalley in collaboration with Prof. Melvin Euerby. Stephan has authored or co-authored 35 peer-reviewed publications, contributed a book chapter, is listed as inventor on 19 patents, and regularly presents his work at international symposia.\u003C/p>","2025-12-29T16:03:03.486Z","75",{"id":1629,"name":1630,"alternativeText":16,"caption":16,"width":1631,"height":1632,"formats":1633,"hash":1646,"ext":1294,"mime":1297,"size":1647,"url":1648,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1649,"updatedAt":1649},97,"unnamed (1).jpg",495,512,{"small":1634,"thumbnail":1640},{"ext":1294,"url":1635,"hash":1636,"mime":1297,"name":1637,"path":16,"size":1638,"width":1639,"height":48},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/small_unnamed_1_7344d8c6f5.jpg","small_unnamed_1_7344d8c6f5","small_unnamed (1).jpg",19.56,483,{"ext":1294,"url":1641,"hash":1642,"mime":1297,"name":1643,"path":16,"size":1644,"width":1645,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_unnamed_1_7344d8c6f5.jpg","thumbnail_unnamed_1_7344d8c6f5","thumbnail_unnamed (1).jpg",3.33,151,"unnamed_1_7344d8c6f5",19.74,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/unnamed_1_7344d8c6f5.jpg","2025-12-29T16:03:00.243Z",[],"-46",{"id":288,"name":1653,"committee":16,"position":16,"affiliation":1654,"email":16,"biography":1655,"createdAt":1656,"updatedAt":1657,"url_path_id":1658,"contactPhoto":1659,"socialLinks":1691,"url_path":1692}," Dwight Stoll","Gustavus Adolphus College, Minnesota","\u003Cp style=\"text-align:justify;\">Dwight Stoll is Professor and Co-Chair of Chemistry at Gustavus Adolphus College in St. Peter, MN. He has authored or co-authored more than 100 peer-reviewed publications and five book chapters in separation science, speaks internationally on the topic, and is co-editor of the recent book: Multi-Dimensional Liquid Chromatography: Principles, practice, and applications. He has also written the monthly “LC Troubleshooting” column for LCGC Magazine since 2017, and co-hosts the Analytically Speaking podcast with Prof. Jim Grinias. His primary research focus is on the development of two-dimensional liquid chromatography (2D-LC) for both targeted and untargeted analyses. Within this area he has made contributions on many aspects of the technique including stationary phase characterization, biopharmaceutical analysis, new 2D-LC methodologies and instrumentation, and fundamental aspects including re-equilibration in gradient elution liquid chromatography and analyte focusing. He has taught several short courses on 2D-LC in recent years at venues including Pittcon and the international HPLC20XX series, and hosts multi-day hands-on trainings for multi-dimensional chromatography in his laboratory at Gustavus.\u003C/p>","2025-07-16T13:04:13.862Z","2025-12-29T16:01:40.836Z","45",{"id":639,"name":1660,"alternativeText":16,"caption":16,"width":1661,"height":1662,"formats":1663,"hash":1687,"ext":1294,"mime":1297,"size":1688,"url":1689,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1690,"updatedAt":1690},"dsclip.jpg",1452,1661,{"large":1664,"small":1670,"medium":1675,"thumbnail":1681},{"ext":1294,"url":1665,"hash":1666,"mime":1297,"name":1667,"path":16,"size":1668,"width":1669,"height":41},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/large_dsclip_88d17f240c.jpg","large_dsclip_88d17f240c","large_dsclip.jpg",96.21,874,{"ext":1294,"url":1671,"hash":1672,"mime":1297,"name":1673,"path":16,"size":1674,"width":42,"height":48},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/small_dsclip_88d17f240c.jpg","small_dsclip_88d17f240c","small_dsclip.jpg",33.41,{"ext":1294,"url":1676,"hash":1677,"mime":1297,"name":1678,"path":16,"size":1679,"width":1680,"height":55},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/medium_dsclip_88d17f240c.jpg","medium_dsclip_88d17f240c","medium_dsclip.jpg",60.89,656,{"ext":1294,"url":1682,"hash":1683,"mime":1297,"name":1684,"path":16,"size":1685,"width":1686,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_dsclip_88d17f240c.jpg","thumbnail_dsclip_88d17f240c","thumbnail_dsclip.jpg",5.9,136,"dsclip_88d17f240c",219.68,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/dsclip_88d17f240c.jpg","2025-07-16T13:03:20.830Z",[],"-19","-54",{"id":5,"session":1695},{"id":5,"title":1696,"teaser":1697,"body":1698,"createdAt":1699,"updatedAt":1700,"publishedAt":1701,"url_path_id":1702,"contacts":1703,"url_path":1733},"Practical LC-MS/MS Method Development","\u003Cp style=\"text-align:justify;\">This course provides hands-on training for practicing scientists, guiding participants step by step through the concepts and techniques required to develop LC-MS/MS methods. The focus is on practical issues related to developing LC-MS/MS methods for small molecules, with an emphasis on problem-solving skills drawn from real-world examples in the pharmaceutical industry and related fields. Participants will gain an updated overview and solid working knowledge of LC-MS/MS, including theoretical concepts, instrumental fundamentals, operating principles, column basics and selection, and key applications. Upon completion, participants will be equipped to independently develop their own LC-MS/MS methods. The course will also introduce emerging technologies and techniques such as monolithic chromatography and hydrophilic interaction liquid chromatography (HILIC). Since many attendees may work in the pharmaceutical industry, relevant concepts of regulation and validation under GLP and GMP will be discussed.\u003C/p>","\u003Cp style=\"text-align:justify;\">Who Should Attend\u003Cbr>\u003Cbr>This one-day course is designed for analytical chemists, supervisors, laboratory managers, and researchers using LC-MS/MS. It is suitable for scientists at all levels - from recent graduates to experienced professionals in the analytical sciences.\u003C/p>","2025-12-29T16:13:41.312Z","2026-01-07T19:47:52.671Z","2025-12-29T16:13:42.635Z","84",[1704],{"id":238,"name":1705,"committee":16,"position":16,"affiliation":1706,"email":16,"biography":1707,"createdAt":1708,"updatedAt":1709,"url_path_id":1710,"contactPhoto":1711,"socialLinks":1731,"url_path":1732},"Perry Wang","US FDA","\u003Cp style=\"text-align:justify;\">Dr. Perry G. Wang has been a chemist at the U.S. Food and Drug Administration (FDA) since 2008. Prior to joining the FDA, he worked in the pharmaceutical and medical device industries. He earned his Ph.D. from Oregon State University and specializes in LC–MS method development and validation for drugs, cosmetics, foods, and dietary supplements. He has been invited to teach this course at Pittcon since 2006, HPLC since 2010, the Eastern Analytical Symposium since 2012, ASMS since 2015, and ACS since 2009. He teaches these courses in his personal capacity as a scientist and not as an employee or representative of the FDA.\u003C/p>","2025-12-29T16:04:26.444Z","2026-01-07T19:47:04.201Z","76",{"id":1712,"name":1713,"alternativeText":16,"caption":16,"width":55,"height":1714,"formats":1715,"hash":1727,"ext":1294,"mime":1297,"size":1728,"url":1729,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1730,"updatedAt":1730},98,"medium_Perry_Wang_43813929c1.jpg",662,{"small":1716,"thumbnail":1721},{"ext":1294,"url":1717,"hash":1718,"mime":1297,"name":1719,"path":16,"size":1720,"width":48,"height":32},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/small_medium_Perry_Wang_43813929c1_92a27cb887.jpg","small_medium_Perry_Wang_43813929c1_92a27cb887","small_medium_Perry_Wang_43813929c1.jpg",28.07,{"ext":1294,"url":1722,"hash":1723,"mime":1297,"name":1724,"path":16,"size":1725,"width":1726,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_medium_Perry_Wang_43813929c1_92a27cb887.jpg","thumbnail_medium_Perry_Wang_43813929c1_92a27cb887","thumbnail_medium_Perry_Wang_43813929c1.jpg",4.84,177,"medium_Perry_Wang_43813929c1_92a27cb887",61.74,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/medium_Perry_Wang_43813929c1_92a27cb887.jpg","2025-12-29T16:04:22.486Z",[],"-47","-55",{"id":29,"session":1735},{"id":29,"title":1736,"teaser":1737,"body":1738,"createdAt":1739,"updatedAt":1740,"publishedAt":1741,"url_path_id":1742,"contacts":1743,"url_path":1766},"Introduction to Artificial Intelligence for Liquid-phase Separations","\u003Cp style=\"text-align:justify;\">Artificial intelligence (AI) is increasingly shaping scientific research and technological development. From advances in molecular discovery to the rapid evolution of data-driven modeling and language-based systems, AI is influencing how knowledge is generated, evaluated, and applied. In analytical separation science, where experiments routinely produce complex and high-dimensional datasets, these developments create both opportunities and challenges. As a result, there is growing interest in understanding how AI methods can be meaningfully and responsibly applied within liquid-phase separations.\u003C/p>","\u003Cp style=\"text-align:justify;\">This full-day course provides a comprehensive introduction to artificial intelligence in the context of liquid-phase separation techniques. Developed by Dr. Bob W.J. Pirok and Dr. Tijmen S. Bos, the course is designed for both academic and industrial scientists seeking a clear, structured, and realistic understanding of AI concepts relevant to separation science.\u003C/p>\u003Cp style=\"text-align:justify;\">Artificial intelligence, much like chromatography, represents a broad umbrella encompassing a wide range of techniques. The course therefore focuses on the most important and practically relevant approaches, including regression, optimization, pattern recognition, and modern machine learning methods. Emphasis is placed on conceptual understanding rather than algorithmic detail, enabling participants to critically assess when and how specific techniques may be appropriate for their own analytical challenges.\u003C/p>\u003Cp style=\"text-align:justify;\">A key component of the course is a critical examination of the limitations of AI. Although AI has existed for more than half a century, its development has not been linear and has included periods of reduced progress, commonly referred to as “AI winters.” Understanding why earlier expectations were not met, and why certain limitations persist today, is essential for avoiding unrealistic expectations and misapplication. These aspects are explicitly addressed, with attention given to data quality, model assumptions, and the role of domain knowledge in successful AI deployment.\u003C/p>\u003Cp style=\"text-align:justify;\">The course further provides an overview of both successful and less successful applications of AI in liquid chromatography and analytical data analysis. By examining real-world examples, participants gain insight into what AI can realistically contribute to method development, optimization, and data interpretation, as well as where conventional approaches remain preferable. The course concludes with a forward-looking discussion on emerging trends and plausible future developments in AI-driven separations.\u003C/p>\u003Cp style=\"text-align:justify;\">In the final part of the course, participants will engage in an interactive session that demonstrates the practical impact of selected AI concepts. Participants will get the opportunity to explore the effects of AI-based optimization using simulated chromatograms. To actively participate, a Windows laptop capable of installing third-party software is recommended; computational performance may influence responsiveness during the exercises.\u003Cbr>&nbsp;\u003C/p>","2025-12-30T23:55:37.842Z","2025-12-30T23:55:39.810Z","2025-12-30T23:55:39.803Z","94",[1744],{"id":1317,"name":1745,"committee":16,"position":16,"affiliation":1746,"email":16,"biography":1747,"createdAt":1748,"updatedAt":1748,"url_path_id":1749,"contactPhoto":1750,"socialLinks":1764,"url_path":1765},"Tijmen Bos","IDEAS","\u003Cp style=\"text-align:justify;\">Dr. Tijmen S. Bos obtained his Ph.D. in 2023 from Vrije Universiteit Amsterdam, where his research focused on automated method development, chemometrics, and advanced data analysis for liquid chromatography, with a particular emphasis on polymer characterization. He subsequently conducted postdoctoral research at the University of Amsterdam, where he worked on data-driven approaches for liquid-phase separations, including algorithm development for chromatographic optimization and the interpretation of complex, high-dimensional analytical data. Building on his academic expertise, Dr. Tijmen S. Bos founded “Innovative Data Evaluation And Separations” (IDEAS), a startup that translates advanced separation science and data-analysis methodologies into practical solutions for industry and research laboratories. Through IDEAS, he develops tailored analytical workflows, optimization strategies, and training programs that bridge fundamental research and real-world analytical challenges.\u003C/p>","2025-12-30T23:54:30.529Z","93",{"id":1751,"name":1752,"alternativeText":16,"caption":16,"width":1753,"height":1753,"formats":1754,"hash":1760,"ext":35,"mime":38,"size":1761,"url":1762,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1763,"updatedAt":1763},104,"unnamed.png",327,{"thumbnail":1755},{"ext":35,"url":1756,"hash":1757,"mime":38,"name":1758,"path":16,"size":1759,"width":937,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_unnamed_20aa7c096e.png","thumbnail_unnamed_20aa7c096e","thumbnail_unnamed.png",59.13,"unnamed_20aa7c096e",54.62,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/unnamed_20aa7c096e.png","2025-12-30T23:54:03.881Z",[],"-64","-65",{"id":1465,"session":1768},{"id":896,"title":1769,"teaser":1770,"body":1771,"createdAt":1772,"updatedAt":1773,"publishedAt":1774,"url_path_id":1775,"contacts":1776,"url_path":1818},"Analysis of Oligonucleotide Therapeutics","\u003Cp style=\"text-align:justify;\">Oligonucleotides are a novel class of drugs with the potential to treat a wide spectrum of indications, including cancer, cardiovascular and metabolic conditions, neurological disorders, pulmonary and ophthalmic diseases. Several different modalities using oligonucleotides to treat disease have been successfully employed, e.g., antisense, siRNA, aptamer, CRISPR, and mRNA, with an increasing number of drug approvals in recent years.&nbsp;\u003C/p>","\u003Cp style=\"text-align:justify;\">The discovery, development, and manufacturing of oligonucleotide drugs necessitates the characterization and monitoring of the main drug component and its impurities by appropriate analytical techniques. The course will cover a wide variety of analytical techniques useful for this class of molecules like determination of assay, purity and the impurity profile of oligonucleotide therapeutics, confirmation of identity / sequence, examination of diastereoisomeric composition, analysis of starting materials and process intermediates, separation of positional isomers of impurities, and approaches for structural elucidation of product-related impurities.\u003C/p>","2026-02-04T23:01:12.871Z","2026-02-04T23:01:15.324Z","2026-02-04T23:01:15.316Z","152",[1777],{"id":1531,"name":1778,"committee":16,"position":16,"affiliation":1779,"email":16,"biography":1780,"createdAt":1781,"updatedAt":1781,"url_path_id":1782,"contactPhoto":1783,"socialLinks":1816,"url_path":1817},"Claus Rentel","Ionis Pharmaceuticals, Inc.","\u003Cp style=\"text-align:justify;\">Dr. Rentel is currently Vice President, Analytical Development and Quality Control at Ionis Pharmaceuticals, Inc., Carlsbad, California. Prior to joining Ionis in 2001 he worked in Quality Control and Special Analytics at CarboGen in Switzerland. He received his Ph.D. (summa cum laude) from the University of Tuebingen, Germany.\u003C/p>\u003Cp style=\"text-align:justify;\">Dr. Rentel has more than 25 years of experience in Quality Control. He has extensive expertise in the CMC development of oligonucleotide therapeutics and is an expert in mass spectrometric techniques. He has been responsible for IND filings of more than 60 oligonucleotides and participated in the NDA filings for the approved oligonucleotide drugs KYNAMRO®, SPINRAZATM, WAYLIVRA®, TEGSEDITM, WAINUATM, TRYNGOLZATM, and DAWNZERATM.\u003Cbr>&nbsp;\u003C/p>","2026-01-21T21:53:22.626Z","126",{"id":1784,"name":1785,"alternativeText":16,"caption":16,"width":1786,"height":1787,"formats":1788,"hash":1812,"ext":1294,"mime":1297,"size":1813,"url":1814,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1815,"updatedAt":1815},126,"23_CSP_Claus-Rentel_3732-Edit-web.jpg",2000,1333,{"large":1789,"small":1795,"medium":1801,"thumbnail":1806},{"ext":1294,"url":1790,"hash":1791,"mime":1297,"name":1792,"path":16,"size":1793,"width":41,"height":1794},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/large_23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61.jpg","large_23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61","large_23_CSP_Claus-Rentel_3732-Edit-web.jpg",38.23,667,{"ext":1294,"url":1796,"hash":1797,"mime":1297,"name":1798,"path":16,"size":1799,"width":48,"height":1800},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/small_23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61.jpg","small_23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61","small_23_CSP_Claus-Rentel_3732-Edit-web.jpg",12.18,333,{"ext":1294,"url":1802,"hash":1803,"mime":1297,"name":1804,"path":16,"size":1805,"width":55,"height":48},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/medium_23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61.jpg","medium_23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61","medium_23_CSP_Claus-Rentel_3732-Edit-web.jpg",23.43,{"ext":1294,"url":1807,"hash":1808,"mime":1297,"name":1809,"path":16,"size":1810,"width":1811,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61.jpg","thumbnail_23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61","thumbnail_23_CSP_Claus-Rentel_3732-Edit-web.jpg",4.1,234,"23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61",197.21,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/23_CSP_Claus_Rentel_3732_Edit_web_6a896d8e61.jpg","2026-01-21T21:53:08.605Z",[],"-92","-116",{"id":86,"session":1820},{"id":86,"title":1821,"teaser":1822,"body":1823,"createdAt":1824,"updatedAt":1825,"publishedAt":1826,"url_path_id":1827,"contacts":1828,"url_path":1851},"Supercritical Fluid Chromatography","\u003Cp style=\"text-align:justify;\">This course will focus on fundamentals and advances in supercritical fluid chromatography (SFC) employing carbon dioxide-based mobile phases. Emphasis will be directed toward pharmaceuticals and will touch on other fields where SFC currently plays or will play a critical role such as lipidomics, specialty chemicals and polymers, biodiesel, foods and vitamins, natural products, and flavors/fragrances.\u003C/p>","\u003Cp>Example applications in these areas will be used throughout the course as teaching illustrations. Attendees will gain the following knowledge:\u003C/p>\u003Cul>\u003Cli>Fundamentals of CO2-based mobile phases – why do SFC?\u003C/li>\u003Cli>Practical advantages of SFC &amp; SFE over GC-based and HPLC-based separations – speed, cost, selectivity, etc.\u003C/li>\u003Cli>An understanding of SFC instrumentation and differences between SFC and HPLC equipment\u003C/li>\u003Cli>Method development in analytical-scale SFC and preparative-scale SFC - special considerations for scale-up\u003C/li>\u003Cli>Fundamentals of chiral SFC separations\u003C/li>\u003Cli>How to choose stationary phases for achiral and chiral SFC separations\u003C/li>\u003Cli>Which mixtures are suitable for SFC, and which mixtures may not be suitable?\u003C/li>\u003Cli>The role of modifiers/entrainers and additives in SFC and SFE separations\u003C/li>\u003Cli>What are the latest developments and what is the future of SFC?\u003C/li>\u003C/ul>","2025-12-29T16:14:45.093Z","2025-12-29T16:14:46.312Z","2025-12-29T16:14:46.307Z","85",[1829],{"id":363,"name":1830,"committee":16,"position":16,"affiliation":1831,"email":16,"biography":1832,"createdAt":1833,"updatedAt":1833,"url_path_id":1834,"contactPhoto":1835,"socialLinks":1849,"url_path":1850},"Larry Miller","Novartis","\u003Cp style=\"text-align:justify;\">Larry Miller is an Associate Director in the Discovery Analytical group at Novartis in Cambridge, MA. He has spent his career performing small molecule achiral and chiral analysis and purifications at the microgram to multi-kg scale. At Novartis, Larry manages a group responsible for analytical and purification support to the Global Discovery Chemistry function. Previously he spent 20 years at Searle/Pharmacia, and 20 years at Amgen. Larry has over 45 peer-reviewed publications and over 45 presentations at scientific meetings and he has served as co-instructor for SFC short courses in the US, Europe, and Asia. He earned his master’s in chemistry from Roosevelt University and his bachelor’s in chemistry from the University of Illinois at Urbana-Champaign.\u003C/p>","2025-12-29T16:05:36.684Z","77",{"id":1836,"name":1837,"alternativeText":16,"caption":16,"width":1838,"height":48,"formats":1839,"hash":1845,"ext":1294,"mime":1297,"size":1846,"url":1847,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1848,"updatedAt":1848},99,"small_Larry_Miller_Headshot_2_76ae06a773.jpg",463,{"thumbnail":1840},{"ext":1294,"url":1841,"hash":1842,"mime":1297,"name":1843,"path":16,"size":1844,"width":559,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_small_Larry_Miller_Headshot_2_76ae06a773_4f309a26d3.jpg","thumbnail_small_Larry_Miller_Headshot_2_76ae06a773_4f309a26d3","thumbnail_small_Larry_Miller_Headshot_2_76ae06a773.jpg",5.76,"small_Larry_Miller_Headshot_2_76ae06a773_4f309a26d3",44.71,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/small_Larry_Miller_Headshot_2_76ae06a773_4f309a26d3.jpg","2025-12-29T16:05:34.814Z",[],"-48","-56",{"id":69,"session":1853},{"id":69,"title":1854,"teaser":1855,"body":1856,"createdAt":1857,"updatedAt":1858,"publishedAt":1859,"url_path_id":1860,"contacts":1861,"url_path":1901},"Sample Preparation and Extraction for LC Workflows","\u003Cp style=\"text-align:justify;\">This short course provides an overview of sample preparation and extraction strategies for LC-amenable analytes across diverse matrices, including environmental, biological, pharmaceutical, and food samples. The focus will be on selecting appropriate workflows to isolate, enrich, and clean up targeted compounds, particularly non-volatile organics, polar and ionic species and small biomolecules.\u003C/p>","\u003Cp style=\"text-align:justify;\">Participants will learn the fundamentals and practical considerations behind commonly used techniques such as solid-phase and liquid–liquid extractions, protein precipitation, and dispersive approaches, as well as emerging miniaturized and high-throughput formats. Attention will be given to optimizing recovery, reducing matrix effects, and ensuring compatibility with LC and LC–MS systems. The course is designed to support analysts in improving data quality, robustness, and sensitivity in downstream LC measurements through effective sample preparation decisions.\u003C/p>","2025-12-29T16:15:44.250Z","2025-12-29T16:15:45.736Z","2025-12-29T16:15:45.731Z","86",[1862],{"id":276,"name":1863,"committee":16,"position":16,"affiliation":1864,"email":16,"biography":1865,"createdAt":1866,"updatedAt":1867,"url_path_id":1868,"contactPhoto":1869,"socialLinks":1899,"url_path":1900},"Emanuela Gionfriddo","University at Buffalo","\u003Cp style=\"text-align:justify;\">Emanuela Gionfriddo is an Associate Professor in the Department of Chemistry at the University at Buffalo, The State University of New York. Her research is centered on the development of advanced analytical separation techniques for complex biological and environmental samples, with a strong emphasis on green extraction methodologies and sustainable analytical chemistry. Dr. Gionfriddo earned her Ph.D. in Analytical Chemistry from the University of Calabria (Italy) in 2013 and subsequently joined the group of Prof. Janusz Pawliszyn at the University of Waterloo (Canada) as a Postdoctoral Fellow and manager of the Gas Chromatography section in the Industrially Focused Analytical Research Laboratory (InFAReL). Her work has been recognized with the 2024 Chinese American Chromatography Association Young Investigator Award, 2023 LCGC Emerging Leader in Chromatography Award, 2023 Eastern Analytical Symposium Young Investigator Award, and the 2022 ACS Analytical Division Satinder Ahuja Award for Young Investigators in Separation Science. Dr. Gionfriddo currently serves as Chair of the ACS Analytical Chemistry Subdivision on Chromatography and Separation Chemistry and associate editor for Journal of Separation Science and Separation Science Plus (Wiley).\u003C/p>","2025-07-15T16:28:22.415Z","2025-12-29T16:06:06.828Z","44",{"id":1870,"name":1871,"alternativeText":16,"caption":16,"width":1872,"height":1873,"formats":1874,"hash":1895,"ext":1294,"mime":1297,"size":1896,"url":1897,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1898,"updatedAt":1898},58,"233A2432.jpg",3600,2401,{"large":1875,"small":1880,"medium":1885,"thumbnail":1890},{"ext":1294,"url":1876,"hash":1877,"mime":1297,"name":1878,"path":16,"size":1879,"width":41,"height":1794},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/large_233_A2432_e7a5539d10.jpg","large_233_A2432_e7a5539d10","large_233A2432.jpg",48.3,{"ext":1294,"url":1881,"hash":1882,"mime":1297,"name":1883,"path":16,"size":1884,"width":48,"height":1800},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/small_233_A2432_e7a5539d10.jpg","small_233_A2432_e7a5539d10","small_233A2432.jpg",15.47,{"ext":1294,"url":1886,"hash":1887,"mime":1297,"name":1888,"path":16,"size":1889,"width":55,"height":48},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/medium_233_A2432_e7a5539d10.jpg","medium_233_A2432_e7a5539d10","medium_233A2432.jpg",29.84,{"ext":1294,"url":1891,"hash":1892,"mime":1297,"name":1893,"path":16,"size":1894,"width":1811,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_233_A2432_e7a5539d10.jpg","thumbnail_233_A2432_e7a5539d10","thumbnail_233A2432.jpg",5.28,"233_A2432_e7a5539d10",528.18,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/233_A2432_e7a5539d10.jpg","2025-07-15T16:27:54.139Z",[],"-18","-57",{"id":182,"session":1903},{"id":182,"title":1904,"teaser":1905,"body":1906,"createdAt":1907,"updatedAt":1908,"publishedAt":1909,"url_path_id":1910,"contacts":1911,"url_path":1928},"(u)HPLC Method Development","\u003Cp style=\"text-align:justify;\">This 3-hour course reviews best practices, shortcuts, and tricks of the trade to help pharmaceutical and other scientists become more successful in developing effective HPLC or UHPLC methods (on potency and ICH-compliant stability-indicating assays of pharmaceuticals) using the traditional selectivity-tuning, three-pronged method template, and universal generic gradient method approaches.\u003C/p>","\u003Cp>&nbsp;What will the student learn?\u003C/p>\u003Cul>\u003Cli>The Method Development fundamentals of using reversed-phase UV detections in pharmaceutical analysis – the Why’s…\u003C/li>\u003Cli>The traditional 5-step Approach,&nbsp;according to Snyder, Kirkland, and Glajch\u003C/li>\u003Cli>The 3-pronged Template Approach for Rapid Method Development\u003C/li>\u003C/ul>\u003Cp>The use of a single Universal Generic Gradient Method for pharmaceutical analysis&nbsp;\u003C/p>","2025-12-29T16:16:32.628Z","2025-12-29T16:16:34.281Z","2025-12-29T16:16:34.277Z","87",[1912],{"id":73,"name":1913,"committee":16,"position":16,"affiliation":1914,"email":16,"biography":1915,"createdAt":1916,"updatedAt":1916,"url_path_id":1917,"contactPhoto":1918,"socialLinks":1926,"url_path":1927},"Michael Dong","MWD Consulting","\u003Cp style=\"text-align:justify;\">Dr. Michael W. Dong is a principal consultant at MWD Consulting. He was formerly a Senior Scientist at Genentech, a Research Fellow at Purdue Pharma, and a Senior Staff Scientist at Applied Biosystems/Perkin-Elmer. He holds a Ph.D. in Analytical Chemistry from the City University of New York and has 130+ publications, including a bestselling book on chromatography (HPLC and UHPLC for Practicing Scientists, 2nd Ed., Wiley, 2019).\u003C/p>","2025-12-29T16:07:04.522Z","78",{"id":1919,"name":1920,"alternativeText":16,"caption":16,"width":1921,"height":937,"formats":16,"hash":1922,"ext":1294,"mime":1297,"size":1923,"url":1924,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1925,"updatedAt":1925},100,"thumbnail_Picture1_54c0ee695a.jpg",137,"thumbnail_Picture1_54c0ee695a_d6486349d4",4.65,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_Picture1_54c0ee695a_d6486349d4.jpg","2025-12-29T16:07:01.200Z",[],"-49","-58",{"id":157,"session":1930},{"id":157,"title":1931,"teaser":1932,"body":1933,"createdAt":1934,"updatedAt":1935,"publishedAt":1936,"url_path_id":1937,"contacts":1938,"url_path":1960},"Multi-Detector Size-Based Separations: SEC, HDC, and flow FFF","\u003Cp style=\"text-align:justify;\">This course will cover the fundamentals and select applications of size-exclusion chromatography (SEC), hydrodynamic chromatography (HDC), and flow field-flow fractionation (flow FFF) methods including asymmetrical flow FFF (AF4) and hollow-fiber flow FFF (HF5). The true power of these methods comes from their coupling to a multiplicity of physical and chemical detection methods, including but not limited to static and dynamic light scattering, viscometry, refractometry, fluorescence, UV/vis, NMR, MS, etc.\u003C/p>","\u003Cp style=\"text-align:justify;\">These couplings will also be examined, in each case by way of individual example and, in select cases, with a minimum of underlying theory. The ultimate aim of this course is to convey how SEC, HDC, and flow FFF separate analytes (macromolecules and colloids), why one would want to employ these methods, what their relative advantages and shortcomings are with respect to one another, and the different and oftentimes complementary views of macromolecules obtained through the use of multiple detectors.\u003C/p>","2025-12-29T16:17:19.046Z","2025-12-29T16:17:20.423Z","2025-12-29T16:17:20.417Z","88",[1939],{"id":232,"name":1940,"committee":16,"position":16,"affiliation":1941,"email":16,"biography":1942,"createdAt":1943,"updatedAt":1943,"url_path_id":1944,"contactPhoto":1945,"socialLinks":1958,"url_path":1959},"André Striegel","National Institute of Standards and Technology (NIST)","\u003Cp style=\"text-align:justify;\">André Striegel holds a B.S. in Chemistry and Ph.D. in Analytical Chemistry, both from the University of New Orleans. After a post-doc at the USDA National Center for Agricultural Utilization Research, he worked in industry, with Solutia (now part of Eastman Chemical). André then moved to academia, as assistant professor of both analytical and materials chemistry at Florida State University. In 2011, he joined the National Institute of Standards and Technology (NIST), where he is currently Scientific Advisor in the Chemical Sciences Division. André is the author of 100 peer-reviewed publications and several books, including the second edition of “Modern Size-Exclusion Liquid Chromatography” and, most recently, “Macromolecular Separation Science.” He is past associate editor of the Encyclopedia of Analytical Chemistry and, since 2015, co-editor-in-chief of Chromatographia. In addition to having been the inaugural Professor in Residence for Preservation Research and Testing at the US Library of Congress, André has managed to hoodwink various organizations into giving him awards and lives in constant fear of being asked to return these. His current visage retains some similarity to the attached photo.\u003C/p>","2025-12-29T16:08:27.797Z","79",{"id":1226,"name":1946,"alternativeText":16,"caption":16,"width":1947,"height":48,"formats":1948,"hash":1954,"ext":1294,"mime":1297,"size":1955,"url":1956,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1957,"updatedAt":1957},"small_Andre_Striegel_photo_5a9d1aa52d.jpg",493,{"thumbnail":1949},{"ext":1294,"url":1950,"hash":1951,"mime":1297,"name":1952,"path":16,"size":1953,"width":1364,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_small_Andre_Striegel_photo_5a9d1aa52d_cc54a5e201.jpg","thumbnail_small_Andre_Striegel_photo_5a9d1aa52d_cc54a5e201","thumbnail_small_Andre_Striegel_photo_5a9d1aa52d.jpg",4.29,"small_Andre_Striegel_photo_5a9d1aa52d_cc54a5e201",24.06,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/small_Andre_Striegel_photo_5a9d1aa52d_cc54a5e201.jpg","2025-12-29T16:08:14.917Z",[],"-50","-59",{"id":327,"session":1962},{"id":327,"title":1963,"teaser":1964,"body":1965,"createdAt":1966,"updatedAt":1967,"publishedAt":1968,"url_path_id":1969,"contacts":1970,"url_path":2014},"Chiral Chromatography","\u003Cp>\u003Ci>What will be taught? \u003C/i>1) Short basics of stereochemistry and separation of enantiomers; 2) Comparative characteristics of gas chromatography (GC), high-performance liquid chromatography (HPLC), super/sub-critical fluid chromatography (SFC), capillary electrophoresis (CE) and capillary electrochromatography (CEC) from the viewpoint of chiral separations and enantioselective analysis; 3) Non-covalent interactions and the importance of their control for preparation and use of chiral stationary phases and chiral selectors; 4) Currently available chiral columns and chiral selectors for practical problem solving and their comparative characteristics; 5) Some unusual effects in chiral separations; 6) Understanding enantioselective recognition and chiral separations (kinetics, thermodynamics, molecular modeling).\u003C/p>","\u003Cp>\u003Ci>What we hope to convey to the participants?\u003C/i> 1) Understanding of critical differences between achiral and chiral separations; 2) Proper selection of technique for particular problem solving; 3) Proper selection of separation and detection conditions; 3) Understanding of major tools for adjustment and fine tuning of separation process; 4) Adequate interpretation and understanding of separation results; 5) Recent trends in chiral column development and applications.\u003C/p>","2025-12-29T16:18:25.235Z","2026-04-02T17:44:26.916Z","2025-12-29T16:18:26.777Z","89",[1971],{"id":206,"name":1972,"committee":16,"position":16,"affiliation":1973,"email":16,"biography":1974,"createdAt":1975,"updatedAt":1976,"url_path_id":1977,"contactPhoto":1978,"socialLinks":2012,"url_path":2013},"Michael Lämmerhofer","The University of Tübingen, Germany","\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"font-size:1.125rem;\">Michael Lämmerhofer is Full Professor for Pharmaceutical (Bio-)Analysis at the University of Tübingen, Germany (since 2011). He graduated in Pharmaceutical Sciences in 1992 and earned his PhD in Pharmaceutical Chemistry in 1996 at the University of Graz, Austria (supervisor Prof. Wolfgang Lindner). Between 1997 and 2002 he was assistant professor and from 2002 to 2011 associate professor at the University of Vienna, Institute of Analytical Chemistry. Between 1999-2000 he spent a year as post-doctoral researcher at the Department of Chemistry of the University of California, Berkeley (Prof. Frantisek Svec/Prof. Jean M. Fréchet). Since 2007, he has been associate editor of Journal of Separation Science and since 2024 he is editor-in-chief.\u003C/span>\u003C/p>\u003Cp style=\"text-align:justify;\">\u003Cspan style=\"font-size:1.125rem;\">His research interests include bioanalysis (metabolomics and lipidomics), pharmaceutical analysis (impurity profiling, enantioselective analytics), multidimensional separations and biopharmaceuticals analysis (peptides, oligonucleotides, proteins, plasmids), and the development of functionalized separation materials (chiral stationary phases, mixed-mode phases, chemo- &amp; bioaffinity materials, nanoparticles, monoliths).&nbsp;\u003C/span>\u003Cbr>&nbsp;\u003C/p>","2025-11-07T17:24:53.713Z","2026-01-12T21:53:11.475Z","61",{"id":1979,"name":1980,"alternativeText":16,"caption":16,"width":1981,"height":1982,"formats":1983,"hash":2008,"ext":1985,"mime":1297,"size":2009,"url":2010,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":2011,"updatedAt":2011},85,"Portrait Laemmerhofer.jpg.jpeg",7088,8540,{"large":1984,"small":1991,"medium":1997,"thumbnail":2003},{"ext":1985,"url":1986,"hash":1987,"mime":1297,"name":1988,"path":16,"size":1989,"width":1990,"height":41},".jpeg","https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/large_Portrait_Laemmerhofer_jpg_bf9d795322.jpeg","large_Portrait_Laemmerhofer_jpg_bf9d795322","large_Portrait Laemmerhofer.jpg.jpeg",85.83,830,{"ext":1985,"url":1992,"hash":1993,"mime":1297,"name":1994,"path":16,"size":1995,"width":1996,"height":48},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/small_Portrait_Laemmerhofer_jpg_bf9d795322.jpeg","small_Portrait_Laemmerhofer_jpg_bf9d795322","small_Portrait Laemmerhofer.jpg.jpeg",25.16,415,{"ext":1985,"url":1998,"hash":1999,"mime":1297,"name":2000,"path":16,"size":2001,"width":2002,"height":55},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/medium_Portrait_Laemmerhofer_jpg_bf9d795322.jpeg","medium_Portrait_Laemmerhofer_jpg_bf9d795322","medium_Portrait Laemmerhofer.jpg.jpeg",50.76,623,{"ext":1985,"url":2004,"hash":2005,"mime":1297,"name":2006,"path":16,"size":1810,"width":2007,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_Portrait_Laemmerhofer_jpg_bf9d795322.jpeg","thumbnail_Portrait_Laemmerhofer_jpg_bf9d795322","thumbnail_Portrait Laemmerhofer.jpg.jpeg",130,"Portrait_Laemmerhofer_jpg_bf9d795322",2277.59,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/Portrait_Laemmerhofer_jpg_bf9d795322.jpeg","2025-11-07T18:51:20.787Z",[],"-34","-60",{"id":345,"session":2016},{"id":345,"title":2017,"teaser":2018,"body":2019,"createdAt":2020,"updatedAt":2021,"publishedAt":2022,"url_path_id":2023,"contacts":2024,"url_path":2028},"Drug Development, Drug Quality, Regulatory, and Quality Control Processes","\u003Cp style=\"text-align:justify;\">This 3-hour introductory course overviews the pharmaceutical industry, the new drug development process, and drug quality fundamentals, including concepts, regulations, public standards, and best practices in nonclinical development and manufacturing for quality assurance. &nbsp;You will learn the roles of quality control (QC) and chemistry, manufacturing, and control (CMC) drug development process in ensuring drug products' safety, efficacy, and quality. &nbsp;It covers industry-standard processes, including SOPs, quality systems, method qualification/validation, release testing, specifications, and certificates of analysis (COAs). &nbsp;\u003C/p>","\u003Cp>What will the student learn?\u003Cbr>&nbsp;\u003C/p>\u003Cul>\u003Cli>The Pharmaceutical Industry and Drug Development Process\u003C/li>\u003Cli>Drug Quality, CMC Process, and Pharmaceutical Regulations\u003C/li>\u003Cli>Quality Control of Small Molecule Drugs\u003C/li>\u003C/ul>","2025-12-29T16:19:15.804Z","2025-12-29T16:19:17.538Z","2025-12-29T16:19:17.534Z","90",[2025],{"id":73,"name":1913,"committee":16,"position":16,"affiliation":1914,"email":16,"biography":1915,"createdAt":1916,"updatedAt":1916,"url_path_id":1917,"contactPhoto":2026,"socialLinks":2027,"url_path":1927},{"id":1919,"name":1920,"alternativeText":16,"caption":16,"width":1921,"height":937,"formats":16,"hash":1922,"ext":1294,"mime":1297,"size":1923,"url":1924,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":1925,"updatedAt":1925},[],"-61",{"id":14,"session":2030},{"id":14,"title":2031,"teaser":2032,"body":2033,"createdAt":2034,"updatedAt":2035,"publishedAt":2036,"url_path_id":2037,"contacts":2038,"url_path":2060},"Advanced chromatographic strategies for comprehensive characterization of protein biopharmaceuticals","\u003Cp style=\"text-align:justify;\">Protein biopharmaceuticals are macromolecules with a therapeutic effect, which are now increasingly used for the treatment of various diseases including cancer, diabetes, infection, inflammatory, and autoimmune disorders. Protein biopharmaceuticals have a complexity far exceeding that of small molecule drugs. However, to fully benefit from these sophisticated therapies, it is essential to ensure that their quality is consistently high. In this context, advanced analytical techniques are indispensable to ensure batch-to-batch reproducibility, long-term stability under various storage conditions, and the precise detection and quantification of impurities, contaminants and degradation products.\u003C/p>","\u003Cp>This short course will highlight the possibilities offered by all the different modes of chromatography (i.e. RPLC, SEC, IEX, HIC, HILIC) to rapidly and accurately characterize the most important critical quality attributes of protein biopharmaceuticals (e.g., glycosylation, oxidation, deamidation, aggregation, glycation, lysine truncation…). The hyphenation of chromatographic approaches with mass spectrometry as well as the use of 2D-LC approaches will also be covered during the short course. Last but not least, the different levels of analysis of biopharmaceuticals will be discussed, including bottom-up analysis (2-5kDa), middle-up (25-100 kDa), and intact proteins analysis (150 kDa).\u003C/p>\u003Cp style=\"text-align:justify;\">Numerous applications to monoclonal antibodies (mAbs) bispecific antibodies (bsAbs) and antibody-drug conjugates (ADCs) will be used to illustrate the advantages and limitations of these diverse chromatographic approaches.\u003C/p>","2025-12-29T16:19:59.208Z","2025-12-29T16:20:00.548Z","2025-12-29T16:20:00.542Z","91",[2039],{"id":1278,"name":2040,"committee":16,"position":16,"affiliation":2041,"email":16,"biography":2042,"createdAt":2043,"updatedAt":2043,"url_path_id":2044,"contactPhoto":2045,"socialLinks":2058,"url_path":2059},"Davy Guillarme","University of Geneva, Switzerland","\u003Cp style=\"text-align:justify;\">Davy Guillarme, Ph.D. in analytical chemistry from the University of Lyon, France, currently serves as an associate professor at the University of Geneva in Switzerland. With over 370 published journal articles in pharmaceutical analysis and h-index of 83 (Google Scholar), his expertise spans various techniques, including HPLC, UHPLC, HILIC, LC−MS, SFC, SFC-MS, multidimensional LC, and the analysis of biopharmaceuticals. He is an editor of the Journal of Chromatography A and serves on the editorial advisory board of prestigious journals like Trends in Analytical Chemistry, Journal of Chromatography B, Journal of Separation Science, LC−GC International. Guillarme has been honored with the LC-GC Emerging Leader Award in Chromatography (2013), the Jubilee Medal from the Chromatographic Society (2018), the International Award of the Belgian Society of Pharmaceutical Sciences (2022) and the Csaba Horvath memorial award (2025). He has also been listed among the world's most influential analytical scientists by \"Analytical Scientist\" magazine in multiple years.\u003C/p>","2025-12-29T16:10:55.704Z","81",{"id":1416,"name":1752,"alternativeText":16,"caption":16,"width":2046,"height":2047,"formats":2048,"hash":2054,"ext":35,"mime":38,"size":2055,"url":2056,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":2057,"updatedAt":2057},457,423,{"thumbnail":2049},{"ext":35,"url":2050,"hash":2051,"mime":38,"name":1758,"path":16,"size":2052,"width":2053,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_unnamed_f085804ba9.png","thumbnail_unnamed_f085804ba9",36.39,169,"unnamed_f085804ba9",61.37,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/unnamed_f085804ba9.png","2025-12-29T16:10:53.693Z",[],"-52","-62",{"id":138,"session":2062},{"id":138,"title":2063,"teaser":2064,"body":2065,"createdAt":2066,"updatedAt":2067,"publishedAt":2068,"url_path_id":2069,"contacts":2070,"url_path":2094},"Basic Theories and Practice of Hydrophilic Interaction Liquid Chromatography","\u003Cp style=\"text-align:justify;\">Hydrophilic interaction liquid chromatography (HILIC) is uniquely suited to separate polar compounds of biomedical, environmental and pharmaceutical importance. As a mode of liquid chromatography, HILIC differs fundamentally from the more widely employed reversed-phase liquid chromatography (RPLC) both in its underlying retention mechanisms and in its practical implementation. This short course is designed for both graduate students and industrial scientists who seek a solid foundation in HILIC.\u003C/p>","\u003Cp style=\"text-align:justify;\">This course integrates fundamental theories with practical aspects of HILIC, providing participants with a comprehensive understanding of why and how HILIC works. The theoretical portion covers eneral retention behaviors of polar compounds, qualitative and quantitative retention mechanisms, and selectivity evaluation in HILIC systems. &nbsp;The practical component focuses on various types polar stationary phases, solvents and mobile phase additives, and sample preparation considerations. Particular attention is given to common challenges in HILIC, such as reproducibility issues, column equilibration and gradient elution in HILIC. After the short course, the participants will be able to have basic and practical knowledge in HILIC to start method development and trouble shoot applications. By the end of this short course, participants will be able to gain basic understanding of fundamental principles and practical knowledge in HILIC and will be equipped to start method development and troubleshooting of real-world applications. This course provides participants with the essential theoretical background and practical tools needed to confidently apply HILIC in research and industrial settings.\u003C/p>","2025-12-29T16:20:22.014Z","2026-01-07T19:52:07.547Z","2025-12-29T16:20:23.504Z","92",[2071],{"id":1325,"name":2072,"committee":16,"position":16,"affiliation":2073,"email":16,"biography":2074,"createdAt":2075,"updatedAt":2076,"url_path_id":2077,"contactPhoto":2078,"socialLinks":2092,"url_path":2093},"Yong Guo","Fairleigh Dickinson University","\u003Cp style=\"text-align:justify;\">Dr. Yong Guo is Professor of Pharmaceutical Science and Chair of Department of Pharmaceutical Sciences at the College of Pharmacy and Health Sciences, Fairleigh Dickinson University (USA). Dr. Guo holds a Ph. D degree in Analytical Chemistry from the State University of New York at Buffalo as well as an MBA degree in Pharmaceutical Management from Fairleigh Dickinson University. Before returning to academia, Dr. Guo spent almost 15 years developing innovative and generic drugs in pharmaceutical industries and contributed to the development and regulatory approval of several innovative drugs. Dr. Guo’s research interest includes chromatographic theories, in-vitro drug release, drug stability and quality assessment. Dr. Guo has over 25 years of experiences in conducting research and developing applications in HILIC and has published almost 20 research and review articles on HILIC.\u003C/p>","2025-12-29T16:11:22.762Z","2026-01-07T19:50:50.812Z","82",{"id":2079,"name":1752,"alternativeText":16,"caption":16,"width":2080,"height":2081,"formats":2082,"hash":2088,"ext":35,"mime":38,"size":2089,"url":2090,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":2091,"updatedAt":2091},108,375,469,{"thumbnail":2083},{"ext":35,"url":2084,"hash":2085,"mime":38,"name":1758,"path":16,"size":2086,"width":2087,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_unnamed_03fed94b50.png","thumbnail_unnamed_03fed94b50",37.06,125,"unnamed_03fed94b50",63.68,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/unnamed_03fed94b50.png","2026-01-07T19:50:24.764Z",[],"-53","-63",{"id":122,"session":2096},{"id":122,"title":2097,"teaser":2098,"body":2099,"createdAt":2100,"updatedAt":2101,"publishedAt":2102,"url_path_id":2103,"contacts":2104,"url_path":2146},"Advanced Topics in HPLC","\u003Cp style=\"text-align:justify;\">This course is designed for scientists who already have some hands-on experience with HPLC. General courses typically focus on general chromatographic theory, reversed phase LC separations, and the basics of HPLC instrumentation and data interpretation. In this half-day tutorial, other separation modes (including HILIC, ion-exchange chromatography, and size-exclusion chromatography) and other types of detectors (including \"universal\" detection modes and mass spectrometry) will be discussed. Additionally, in-depth details on instrument design and strategies for method development in a broad array of application areas will be provided.&nbsp;\u003C/p>","\u003Cp style=\"text-align:justify;\">By the end of this course, students will have a better understanding of:\u003Cbr>- HPLC system design, the importance of proper instrument set-up on chromatographic performance, and ways to ensure suitable performance over time;\u003Cbr>- the appropriate separation and detection modes for a wide variety of sample types so that analyte selectivity and response are maximized;\u003Cbr>- approaches to method development, including software-based methods, that will reduce analytical development times; and,\u003Cbr>- the basics of HPLC troubleshooting when problems arise.\u003Cbr>&nbsp;\u003C/p>","2026-01-07T20:03:24.476Z","2026-04-01T20:03:40.945Z","2026-01-07T20:57:21.742Z","98",[2105],{"id":193,"name":2106,"committee":16,"position":16,"affiliation":2107,"email":16,"biography":2108,"createdAt":2109,"updatedAt":2110,"url_path_id":2111,"contactPhoto":2112,"socialLinks":2144,"url_path":2145},"Jim Grinias","Rowan University, Glassboro, New Jersey","\u003Cp style=\"text-align:justify;\">James Grinias is a Professor in the Department of Chemistry &amp; Biochemistry at Rowan University in Glassboro, NJ. Dr. Grinias has a number of research interests focused on chemical separations and microfluidics, both at the fundamental level and for the analysis of biological systems. &nbsp;He is the recipient of the 2021 American Chemical Society Satinder Ahuja Award for Young Investigators in Separation Science and the 2022 LCGC Emerging Leader in Chromatography. At Rowan, he teaches courses in general, analytical, and bioanalytical chemistry while also conducting research on UHPLC column performance and instrument miniaturization.\u003C/p>","2025-06-03T16:05:13.138Z","2026-01-07T19:56:08.362Z","39",{"id":1531,"name":2113,"alternativeText":16,"caption":16,"width":2114,"height":2115,"formats":2116,"hash":2140,"ext":1294,"mime":1297,"size":2141,"url":2142,"previewUrl":16,"provider":24,"provider_metadata":16,"createdAt":2143,"updatedAt":2143},"Grinias_2021Headshot_JPEG.jpg",1252,1520,{"large":2117,"small":2122,"medium":2128,"thumbnail":2134},{"ext":1294,"url":2118,"hash":2119,"mime":1297,"name":2120,"path":16,"size":1416,"width":2121,"height":41},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/large_Grinias_2021_Headshot_JPEG_5f7183660c.jpg","large_Grinias_2021_Headshot_JPEG_5f7183660c","large_Grinias_2021Headshot_JPEG.jpg",824,{"ext":1294,"url":2123,"hash":2124,"mime":1297,"name":2125,"path":16,"size":2126,"width":2127,"height":48},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/small_Grinias_2021_Headshot_JPEG_5f7183660c.jpg","small_Grinias_2021_Headshot_JPEG_5f7183660c","small_Grinias_2021Headshot_JPEG.jpg",32.22,412,{"ext":1294,"url":2129,"hash":2130,"mime":1297,"name":2131,"path":16,"size":2132,"width":2133,"height":55},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/medium_Grinias_2021_Headshot_JPEG_5f7183660c.jpg","medium_Grinias_2021_Headshot_JPEG_5f7183660c","medium_Grinias_2021Headshot_JPEG.jpg",63.29,618,{"ext":1294,"url":2135,"hash":2136,"mime":1297,"name":2137,"path":16,"size":2138,"width":2139,"height":937},"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/thumbnail_Grinias_2021_Headshot_JPEG_5f7183660c.jpg","thumbnail_Grinias_2021_Headshot_JPEG_5f7183660c","thumbnail_Grinias_2021Headshot_JPEG.jpg",4.98,128,"Grinias_2021_Headshot_JPEG_5f7183660c",212.52,"https://confcats-siteplex.s3.us-east-1.amazonaws.com/hplc26/Grinias_2021_Headshot_JPEG_5f7183660c.jpg","2025-06-03T16:05:10.928Z",[],"-14","-69",{"data":2148,"meta":2149},{"id":257,"heading":252,"createdAt":258,"updatedAt":259,"publishedAt":260,"url_path_id":261,"url_path":253,"contentType":120},{},1792782831815]